erythropoiesis相关论文
Mapping Human Pluripotent Stem Cell-derived Erythroid Differentiation by Single-cell Transcriptome A
There is an imbalance between the supply and demand of functional red blood cells (RBCs) in clinical appli-cations. This......
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ASXL1 mutations are found in a spectrum of myeloid malignancies with poor prognosis.It is reported that Asxl1+/-mice dev......
Introduction Obstructive sleep apnea(OSA)is characterized by recurrent intermittent hypoxia during sleep.Hypoxia and gen......
Erythropoiesis is the process by which hematopoietic stem cells proliferate and differentiate through multiple stages to......
Cab39/AMPK/mTOR pathway mediates p53-independent erythroid apoptosis in miR-144/451-/-mice upon stre
Abnormal regulation of small noncoding RNAs,or microRNAs (miRs) has been implicated in the pathophysiology of various hu......
The bicistronic microRNA locus miR-144/451 is strongly expressed during erythropoiesis and facilitates cellular maturati......
Dynamic changes of murine bone marrow, spleen and liver erythropoiesis as well as red cell parameter
Bone marrow,spleen and liver are three key erythropoietic tissues in mammals.In the mouse,it is well established that th......
U2AF1 (U2AF35) is the small subunit of the U2 auxiliary factor (U2AF) which constitutes the U2 snRNP (small nuclear ribo......
Myelodysplastic syndromes (MDS) are clonal hematopoietic stem cell heterogeneous disorders characterized by dysplasia of......
Erythrocyte development is a complex process which contains erythroid progenitors burst-forming unit-erythroid (BFU-E),c......
TET family proteins (TET1,TET2 and TET3) have recently emerged as important epigenetic modifiers by catalyzing the conve......
Introduction Obstructive sleep apnea is characterized by recurrent intermittent hypoxia.Hypoxia and gender are both asso......
Cell sorting based method is widely used to screen clusters of cells during a complete biological process.We applied thi......
We study numerically existence of invariant and ergodic measures in the model of dynamics of blood-forming system.Existe......
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Genome-wide analysis of the zebrafish Klf family identifies two genes important for erythroid matura
Krüppel-like transcription factors (Klfs), each of which contains a CACCC-box binding domain, have been investigate......
巨噬细胞在红系生成的动态平衡中,主要作用是促进有核红细胞分化成熟为网织红细胞,并清除衰老的红细胞.近期的小鼠实验证明,红系造......
Does Carica papaya leaf-extract increase the platelet count? An experimental study in a murine model
Objective:To investigate the potential role of fresh Carica papaya (C. papaya) leaf extract on haematological and bioche......
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In the past two decades,purinergic signaling has emerged as a key regulator of hematopoiesis in physiological and pathol......
Prolactin is a multifunctional hormone that exerts many separate functions and acts as an important connection between t......
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BACKGROUND:Erythropoiesis is regulated by a range of intrinsic and extrinsic factors,including different cytokines.Recen......
By modulating hepcidin production, an organism controls intestinal iron absorption, iron uptake and mobilization from st......
Kzp Regulates the Transcription of gata2 and pu.1 during Primitive Hematopoiesis in Zebrafish Embryo
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨人巨细胞病毒感染对婴幼儿红细胞系统(简称红系)造血功能的影响.方法 对2007年1至10月收治于我院儿科血液病房的21例伴有......
Objective To investigate whether a-hemoglobin stabilizing protein (AHSP),the a-globin-specific molecular chaperone,is re......
胚胎整体RNA原位杂交显示,BHC80基因表达主要集中在中枢神经系统部位.应用吗啡啉修饰的反义寡核苷酸技术抑制BHC80基因表达,显示胚......
目的利用小鼠盲肠结扎穿刺模型探讨脓毒症对红系造血祖细胞发育的影响。方法将C57BL/6小鼠分成假手术组和脓毒症组,采用盲肠结扎穿......
红细胞发生的研究主要依据于MEL细胞系和分离到的少量的小鼠成红细胞,MEL细胞由Friend病毒转化而来,对促红细胞生成素不敏感,而成红细......
贫血症是在有煽动性的肠疾病(IBD ) 的病人的经常的复杂并发症,并且与生命的减少的质量被联系并且增加了住院的率。联系 IBD 的贫血......
本文对163例健康足月儿生后6个月内红细胞肌酸(EC)、血红蛋白(Hb)、网织红细胞(Retic)三项指标进行动态观察。发现婴儿生后最初6月......
本文通过对63例健康足月儿生后6个月内红细胞肌酸(EC)、血红蛋白(Hb)、血清铁蛋白(SF)、红细胞游离原卟啉(FEP)及(FEP/Hb)等铁代谢......
由 modulating hepcidin 生产,一个有机体从店控制肠的铁吸收,铁举起和动员到会身体铁需要。在最近的年里,在我们也为理解一些人的混......
microRNA为短链非编码RNA,通过与靶基因3’UTR序列互补在转录后水平发挥作用。已有研究表明,mieroRNA在红细胞发生过程中起着重要的......
本研究探讨神经生长因子(NGF)对红系造血的影响及内在机制。采用流式细胞术、祖细胞集落测定、血细胞计数、实时荧光定量PCR及酶联免......
为了探讨人类ERMAP基因在红细胞分化发育过程中的作用,以Ara-C诱导K562细胞向红系方向分化,以十二氟波酯钠盐(TPA)诱导K562细胞向......
巨噬细胞在红系生成的动态平衡中,主要作用是促进有核红细胞分化成熟为网织红细胞,并清除衰老的红细胞。近期的小鼠实验证明,红系......
小鼠暴露于低压舱(0.42atm,22h/day)连续9天。结果表明,慢性重复低氧后,小鼠的血清促红细胞生成素(EPO)浓度迅速增高,第3天达峰值,......
促红细胞生成素(erythropoiesis,EPO)是一种调节红细胞生成的造血因子,因其能提高运动员的耐力而倍受体育界各方人士的关注。为此,国......
Mean hemoglobin(Hb) concentration of about 3 500 subjects derived from 17 studies of Himalayan highlanders(Tibetans, She......
采用常规实验血液学方法和造血祖细胞体外培养技术观察了肺泡巨噬细胞培养上清液对早期红系造血祖细胞和晚期红系造血祖细胞的影响......
红系生成及其调节被认为发生于骨髓内的特定结构造血岛。巨噬细胞对红系生成的促进作用及与红系生成龛——造血岛的结构及功能完整......
Pharmacodynamics of CNTO 530 and Darbepoetin-α in Human TNF-α Transgenic Mice, a Murine Model of Ane
CNTO 530 and darbepoetin-a are long lived erythropoietin receptor agonists (ERAs). Clinically, anemia of chronic disease......
Coexistence of chronic kidney disease (CKD) and chronic heart failure (CHF) define a recently recognized clinical entity......
Iron-Restricted Erythropoiesis in Anaemic Patients with Giant Cell Arteritis and Polymyalgia Rheumat
The aim of this observational study was to biochemically characterize the anaemia in GCA (giant cell arteritis) and PMR ......
Normally, cyclin interacts with cyclin-dependent kinase (CDK) to form a cyclin-CDK complex, which promotes cell cycle pr......